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Cristobal L Miranda Selected Research

xanthohumol

12/2021Xanthohumol Pyrazole Derivative Improves Diet-Induced Obesity and Induces Energy Expenditure in High-Fat Diet-Fed Mice.
11/2021Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet-Induced Obese Mice.
1/2021Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARĪ³.
1/2020Improvements in Metabolic Syndrome by Xanthohumol Derivatives Are Linked to Altered Gut Microbiota and Bile Acid Metabolism.
1/2020Targeting the Liver-Brain Axis with Hop-Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice.
3/2019Antiproliferative and Cytotoxic Activity of Xanthohumol and Its Non-Estrogenic Derivatives in Colon and Hepatocellular Carcinoma Cell Lines.
12/2018Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice.
7/2013Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.
6/2013A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.
3/2012Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
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Cristobal L Miranda Research Topics

Disease

8Obesity
12/2021 - 06/2013
6Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2021 - 07/2013
4Neoplasms (Cancer)
01/2020 - 04/2009
3Body Weight (Weight, Body)
11/2021 - 07/2013
3Insulin Resistance
11/2021 - 12/2018
3Cardiovascular Diseases (Cardiovascular Disease)
03/2020 - 03/2012
2Type 2 Diabetes Mellitus (MODY)
01/2020 - 03/2012
2Cognitive Dysfunction
01/2020 - 12/2018
2Inflammation (Inflammations)
01/2020 - 01/2016
1Weight Gain
12/2021
1Hyperglycemia
04/2020
1Hypertriglyceridemia
04/2020
1Hyperinsulinism (Hyperinsulinemia)
04/2020
1Osteosarcoma (Osteogenic Sarcoma)
01/2020
1Hypoxia (Hypoxemia)
01/2020
1Hepatocellular Carcinoma (Hepatoma)
03/2019
1Liver Neoplasms (Liver Cancer)
03/2019
1Fatigue
09/2018
1Chest Pain (Chest Pains)
01/2018
1Angina Pectoris
01/2018
1Ascorbic Acid Deficiency (Vitamin C Deficiency)
02/2012
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2010
1Leukemia
05/2009
1Adenocarcinoma
04/2009
1Colonic Neoplasms (Colon Cancer)
04/2009
1Parkinson Disease (Parkinson's Disease)
10/2007
1Neuroblastoma
10/2007
1Prostatic Neoplasms (Prostate Cancer)
02/2007
1Hyperplasia
02/2007

Drug/Important Bio-Agent (IBA)

11xanthohumolIBA
12/2021 - 02/2007
8Glucose (Dextrose)FDA LinkGeneric
12/2021 - 07/2013
6FlavonoidsIBA
01/2020 - 03/2012
2Insulin (Novolin)FDA Link
11/2021 - 09/2018
2Triglycerides (Triacylglycerol)IBA
04/2020 - 09/2018
2LDL CholesterolIBA
04/2020 - 09/2018
2CeramidesIBA
04/2020 - 01/2020
2Biomarkers (Surrogate Marker)IBA
03/2020 - 07/2013
2Proteins (Proteins, Gene)FDA Link
01/2020 - 04/2009
1pyrazoleIBA
12/2021
1PolyphenolsIBA
11/2021
1Nonesterified Fatty Acids (NEFA)IBA
04/2020
1Folic Acid (Vitamin M)FDA LinkGeneric
03/2020
1HomocysteineIBA
03/2020
1Bile Acids and Salts (Bile Acids)IBA
01/2020
1CollagenIBA
01/2020
1ProteomeIBA
01/2020
1SphingolipidsIBA
01/2020
1EnzymesIBA
03/2019
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
03/2019
18-prenylnaringeninIBA
03/2019
1Phytoestrogens (Phytoestrogen)IBA
03/2019
1Estrogens (Estrogen)FDA Link
12/2018
1CholesterolIBA
09/2018
1LeptinIBA
09/2018
1Nitroglycerin (Dynamite)FDA LinkGeneric
01/2018
1purineIBA
02/2012
1NucleotidesIBA
02/2012
14-oxo-2-nonenalIBA
01/2010
14-hydroxy-2-nonenal (4-hydroxynonenal)IBA
01/2010
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
05/2009
1Proanthocyanidins (Procyanidins)IBA
04/2009
1Anticarcinogenic AgentsIBA
04/2009
1PhytochemicalsIBA
04/2009
1Reactive Oxygen Species (Oxygen Radicals)IBA
04/2009
1RotenoneIBA
10/2007
1PesticidesIBA
10/2007
1epigallocatechin gallate (epigallocatechin-3-gallate)IBA
10/2007

Therapy/Procedure

2Fat-Restricted Diet (Diet, Fat Restricted)
11/2021 - 09/2018
1African Traditional Medicine (Medicine, African)
09/2018
1Oral Administration
01/2016